Some fantastic results to be had, both artificially and professionally for me. The mobos will only get better imo, I'd lookout for some nice MSI/Gigabyte/ASUS releases in the near future.
As a point of personal interest, and just to look up some comparisons on a gaming pov. The purely gaming pc I have based on 775, real decent quad, el crappo memory, 480 and a physx card and a mobo I need to swap out for a spare cos it's stopped liking overclocks (needs a new psu also, but that's besides the point). I quickly installed the benches in the video to see:
3D Vant: P21489, G:19238, P:33107
3D 11: P5114
Heaven: 52.9 fps / Score 1333
Plays all the games on 1920x1200 without issues and massive quality settings, physx and so on.
Gaming wize, I still don't think there's a requirement to upgrade this generation. Of course, if you have to buy new, you have plenty of reasons. Luckily I have spares and sources.