I'll say this, then - when your rig is all looped up etc. and you're ready to start overclocking, make sure you have the latest BIOS.
Then, make sure you have MSI ClickBIOS II installed, or else you can't adjust the vcore at all - it's locked from within the UEFI itself.
Set multi to 44, set vcore to 1.2 and then run Intel Burn Test on its Maximum preset for 10 runs. Have HWMonitor running as well, so you can monitor temps. If it's stable, up the multi to 45, and repeat the tests. When the test is no longer stable, up the vcore by 0.05v and try again. As long as you keep under 1.4v as is expressed by MSI as the safe limit (although I really don't think you'll reach that high) and your maximum core temp is under 75*C after IBT you've done well.
Once you reach the temperature limit of your overclock, you can begin to whittle down the vcore until, once more, IBT is unstable. Bump the vcore up until it is once again stable, and voila! - maximum overclock achieved