A bit of Googling - 1.525v default. 1.55v is good for 3.4ish, 1.6v 3.7ish, some people have had to max this to achieve stability at high clocks 3.7+...
These are just averages taken from various websites, condensed for your ease
As for what is safe -IMO - 1.6v 24/7 with decent airflow...