It can cause instability with no clue. There are tons of people on Asus forums and OC.net that can confirm this. Plus, the uninstall does not get rid of everything. It takes a bit of CC Cleaner and some times manual reg edits to totally wipe the system of the program.
My 3770K rig would BSOD for no reason at all. Drove me nuts trying to track it down. Got rid of AI suite, and problems solved. There are tons of people still reporting the same problem even today.