I'd probably go with an LSI megaraid 8 port card with 256 to 512MB of cache and a battery module. Just make sure the model you pick supports 2TB drives. As far as the RAID level goes, I'd use RAID 6. You will lose the capacity of two drives for the array, but will be able to lose any two drives to failure without having your array fail. RAID 5 is another choice and you will only lose the capacity of one drive for the array, but with that large of an array RAID 5 can sometimes struggle compared to 6.