it would take a bunch of skill. You could slice the heatsink off, than you would need to very carefully remove as much of the epoxy on the GPU core as you could.
You would probably mess up the core.
If you just want it to look cool I was thinking about making a cooler (like the AC ones) out of red plastic but using a 80mm fan to blow over the heatsinks that are already on the cards, than exiting the case like the AC cooler does.