I personally would go for the ASUS board, the EVGA board seems a bit flashy and more targeted at the overkill gamer. You said you're going to be using this as a serious work station for CAD and such right? Also I'm guessing you won't be using SLI on your graphics cards correct? The ASUS boards has what they're calling enhanced parallel GPU computing, EVGA doesn't appear to have a feature like this.
If it were me getting a build like this for a workstation I would opt for the ASUS board.