This is why I don't play games in the first year of their release—or in this case the second. I'd rather wait when hardware has caught up. With a Fury at 1440p, I'd be looking at a mixture of medium and high settings. I didn't expect to have to do that quite so soon—and that's still only 60 FPS. I do wish this was better optimised for AMD hardware.
edit: Though, actually, now that I've looked very closely at the 4k screenshots, there really doesn't appear to be that big of a difference between Medium and Ultra. There is definitely a texture sharpness to the Ultra settings that Medium and High do not have, but there isn't a great deal I can see otherwise.