This one looks really good for the price. I'm sure it would be pretty solid once the panels are attached if you're concerned about that. How often do you move it around though? Will you go custom loop down the track? This and the Define S look great for water cooling.
I had a look at a Define S & an R5 yesterday in the flesh (nothing like getting your hands on one for perspective) and was really impressed. Being slightly isolated means I am yet to see an H440 or any Phanteks. S340 could be a go too I forgot about that until I read Gary's review of this one.
I think either way you go you'd end up with a good looking and performing case that fits your spec. If budget is more important to you than looks (you mentioned the optical cutout) get this.
If the H440 floats your boat then go for it - you really can't go wrong