Maybe there would be a way to get games to play in just the middle lower screen (if you had the 40" screen setup that would be 1337). Then it wouldn't be so bad. If not though, that would definately be tricky!
If you won the lotto you could probably pay off nVidia / ATI to make you a custom gfx setup which would cost you a ****in boatload. But I'm sure they would do it for you for the right price.
First off you would have to win the lottery just to afford the power bill from that thing. It would be great to have thought. Imagine something like 3x3 with 40" monitors Then you wouldn't have to worry about the crosshair in between the monitors, it would be in the dead center