It looks like Diablo IV may be the second major PC game to support DirectStorage

[WYP]

Accelerated storage, shorter loading times, lower CPU overhead. That's DirectStorage



Read more about Diablo IV's beta supporting DirectStorage.

 

[Dicehunter]

Load times during the beta were nothing to write home about so I'm guessing it wasn't active at that time, Hopefully 1.1 will be implemented though.