Sometimes startup issues, fixed by leaving the PSU off for a few minutes, or that occur semi-randomly, can be an issue of transient signals from either interference or capacitance in your cables, some things that could cause this include being near a source of high EM (Microwaves or anything with an AC motor are typical culprits), or particularly long cabling within your PC(Maybe daisy changed extenders?)
That's assuming your PSU is already in good shape, checking the voltage readings on each line from your motherboards a good place to start.
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