The prominent issue is signal integrity. You can see that m.2 slots are just below the CPU. They are very close and, as stated in the article, those are primary m.2 slots with CPU lanes. Also with PCIe x16 slot, only boards that don't support SLI/CF have some support for PCIe 4.0. Again, they have only one PCIe slot that is connected to CPU. Boards that have lane dividers (a bunch of those square chips that you see between PCIe slots) and support for SLI/CF, in this case, higher-end boards, don't support PCIe 4.0. The second slot is very far from the CPU, and lane dividers don't support PCIe 4.0. That why you need better-built PCBs, and different components. ITX boards have extremely densely packed PCBs, with traces going all around everywhere so I assume it is too noisy to keep adequate signal integrity for PCIe 4.0, hence no support.
PCH has nothing to do with support on x470 boards because support is related only to CPU lanes.
If you know very basic stuff about PCIe lanes, and how stuff is organized on the motherboard it is very logical and makes sense.
If there are any engineers there please correct me if I am wrong.