as far as i know you can make profiles for which games to turn crossfire on/off in catalyst control center.
As far as actually building crossfire profiles that optimize crossfire for a certain game those are written and compiled by AMD and source code for them is unavailable for modification, unless you are comfortable with hex editing.
edit: thinking about this a little more you might be able to work something out here if you really want to write software http://developer.amd.com/sdks/Pages/default.aspx
as far as catalyst control center 12.6 beta drivers, click the gaming tab on the left click 3D Application Settings. You can setup the profiles for turning on/off crossfire for specific games there.